High-throughput transcriptomics has advanced through the introduction of TempO-seq, a targeted alternative to traditional RNA-seq. TempO-seq platforms use 50 nucleotide probes, each specifically designed to target a known transcript, thus…
As part of the EUSAAT and ESTIV 2022 meetings, Dr. Ruchir Shah will present recent work on OrbiTox, an interactive 3D visualization and analysis platform for varied scientific big data…
As part of the EUSAAT and ESTIV 2022 meetings, Dr. Ignacio Tripodi will present recent research on turning Adverse Outcome Pathways (AOPs) into testable hypotheses with natural language processing (NLP)…
Our poster titled “Towards Automated Deep Learning Classification of Phase-contrast images from High-throughput Screening Assays” was selected as a Top 10 Abstracts at the Society of Toxicology’s 61st Annual Meeting,…
We are excited to be back at the annual meeting of SOT this year, which is being held in San Diego between March 27-31, 2022. This year, we will be showcasing our work in the following presentations.
Molecular structure-based predictive models provide a proven alternative to costly and inefficient animal testing. However, due to a lack of interpretability of predictive models built with abstract molecular descriptors they…
Dr. Ruchir Shah, Dr. Vijay Gombar, Mr. Austin Ross, and Mr. Eric McAfee of Sciome will give a seminar as part of the Big Data in Environmental Science and Toxicology virtual learning…
High-throughput chemical screening approaches often employ microscopy to capture photomicrographs from multi-well cell culture plates, generating thousands of images that require time-consuming human analysis. To automate this subjective and time-consuming…
Each year, the International Medical Informatics Association (IMIA) Yearbook highlights notable papers in the field of Bioinformatics and Translational Informatics (BTI). After identifying 263 potential papers evaluated on their novelty,…
At ASCCT 2021, Dr. Ruchir Shah will present recent work on best practices for benchmark dose (BMD) analysis of toxicogenomic data and discuss findings from extensive transcriptional dose response analysis using BMDExpress2.3...
At ASCCT 2021, Dr. Brian Howard will present recent work on Sciome's semi-automated PDF text extraction tool, FIDDLE, which uses deep learning, image processing, and NLP to convert binary PDF text documents into machine-readable raw text.
At ASCCT 2021, Dr. Vijay Gombar will highlight recent work on OrbiTox, an interactive 3D visualization and analysis platform for varied scientific big data with special emphasis on predictive toxicology.