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About Us

Sciome LLC is an innovative research and technology consulting company providing state of the art informatics solutions for the life sciences industry. We specialize in developing and deploying novel bioinformatics, cheminformatics, text-mining and data science solutions for researchers in government, academic and private sector organizations.

High throughput technologies are routinely used to study genomes, proteomes and metabolomes creating a deluge of scientific data. In addition, large volumes of data are available via electronic health records, clinical study reports, government reports, high content images, and the ever increasing amount of scientific literature in peer reviewed journals and on the World Wide Web. Success of scientific endeavors in such data rich environments greatly depends on the careful exploration and interpretation of this data. This has created a large demand for sophisticated tools and highly skilled expertise to enable data-driven discovery.

Our goal is to provide cutting edge, customized and cost effective informatics solutions for efficient data management, data analyses and interpretation. We develop novel quantitative methodologies, design and deliver intuitive software tools, and deploy efficient computational techniques to enable timely and insightful discoveries.

Our mission is to enable science via analytical informatics.

What We Do

We use comprehensive and cutting edge quantitative methods paired with efficient informatics techniques to solve complex scientific challenges. We work with our clients at all stages of the life science discovery process, starting with hypotheses generation and experiment design, through data analysis using off-the-shelf and custom designed methodologies and culminating with expert help in interpretation of the results. We also provide detailed support for manuscript preparation, formulation of reports, and aid in the dissemination of information using print or online medium for projects that cover a variety of scientific disciplines. Our consulting team includes PhD level Bioinformatics Scientists, Statisticians, Cheminformaticians, Computational Toxicologists, Health Scientists and Computer Scientists with a wide array of experience in government contracting, academic research and the pharmaceutical industry.



Text-Mining and Literature Review

Data Science and Analytics

Software Development

Satisfied Clients
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Who We Are

We are a light hearted, hardworking, multi-disciplinary team of scientists who enjoy diverse technical challenges and love to work in a team. We share a passion for varied scientific disciplines and we love to learn, experiment and innovate.

The Sciome team has a diverse background in helping organizations and individual scientists succeed in solving scientific challenges.

We develop novel quantitative methodologies, design and deliver intuitive software tools, and deploy efficient computational techniques to enable timely and insightful discoveries.

Who We Serve

We get hired to solve complex, unique and/or recurring scientific challenges. Our consulting engagements range from multiyear research endeavors in support of environmental or health related topics to short term data mining projects in support of specific scientific pursuits. We continue to serve a variety of US Federal Government agencies, pharmaceutical and biotechnology companies, non-profit research organizations and academic institutes.

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Software We Support

SWIFT-Active Screener is a web-based, collaborative systematic review software application. Active Screener was designed to be easy-to-use, incorporating a simple, but powerful, graphical user interface with rich project status updates.

BMDExpress was created for the purpose of providing an easy workflow to transform toxicogenomic data into BenchMark Doses for aggregated collections of genes; KEGG pathways, GO terms, or user defined categories.

SWIFT-Review (SWIFT is an acronym for “Sciome Workbench for Interactive computer-Facilitated Text-mining”) is a freely available interactive workbench which provides numerous tools to assist with problem formulation and literature prioritization.

Comprehensive analysis of TempO-Seq data using novel, validated and robust bioinformatics methods. Upload raw Tempo-Seq data and instantaneously obtain in-depth analysis including cluster plots, principal component plots, differentially expressed gene list, and pathway analysis.

The Integrated Chemical Environment (ICE) provides high-quality, curated data from the National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) and its partners as well as other data resources and tools to support development of new approaches for assessing chemical safety.

OrbiTox presents Big Data in an intuitive, immersive, and fluid 3D environment. It is a one-of-a-kind computational translational discovery platform for interactive, 3D visualization of large (~million objects), high-dimensional (~1000 features), multidomain toxicology and drug discovery data. 

Sciome employs a highly talented team of software engineers and scientific programmers. This development team works closely with Sciome scientists, mathematicians and statisticians to design and implement interactive software solutions that solve important problems on behalf of our clients.

Latest Publications

Hari, A., AbdulHameed, M.D.M., Balik-Meisner, M., Mav, D., Phadke, D.P., Scholl, E.H., Shah, R., Casey, W.M., Auerbach, S., Wallqvist, A. & Pannala, V.R. (2024). Exposure to PFAS chemicals induces sex-dependent alterations in key rate-limiting steps of lipid metabolism in liver steatosis. Frontiers in Toxicology 6 – 2024.

Hogberg, H.T., Tsaioun, K., Breidenbach, J.D., Elmore, B., Filipovska, J., Garcia-Reyero, N., Hargreaves, A.J., Joshi, O., Omeragic, E., Plant, S., Ram, R., Virmani, I., Waspe, J. & Macmillan, D.S. (2024). A systematic scoping review of the neurological effects of COVID-19. Neurotoxicology 2024 May 17:S01610813X(24)00041-X.

Cong, G., Patton, R.M., Chao, F., Svoboda, D.L., Casey, W.M., Schmitt, C.P., Murphy, C., Erickson, J.N., Combs, P. & Auerbach, S.S. (2024)

Ford, L.C., Lin, H-C., Tsai, H-H. D., Zhou, Y-H., Wright, F.A., Sedykyh, A., Shah, R.R., Chiu, W.A. & Rusyn, I. (2024). Hazard and risk characterization of 56 structurally diverse PFAS using a targeted battery of broad coverage assays using six human cell types. Toxicology 503:153763.

Lloyd, D., House, J.S., Akhtari, F.S., Schmitt, C.P., Fargo, D.C., Scholl, E.H., Phillips, J., Choksi, S., Shah, R., Hall, J.E. & Motsinger-Reif, A. (2024). Interactive data sharing for multiple questionnaire-based exposome-wide association studies and exposome correlations in the Personalized Environment and Genes Study. Exposome, Feb 12;4(1):osae003. PMCID: PMC10899804

Lloyd, D., House, J.S., Akhtari, F.S., Schmitt, C.P., Fargo, D.C., Scholl, E.H., Phillips, J., Choksi, S., Shah, R., Hall, J.E. & Motsinger-Reif, A. (2024). Questionnaire-based exposome-wide association studies for common diseases in the personalized environment and genes study. Exposome, osae002.

Latest News


Sciome’s Work Highlighted in NIEHS 2023 Papers of the Year

Every year the National Institute of Environmental Health Sciences (NIEHS) selects a number of exemplary papers of interest for special recognition as Papers of the Year. We are pleased to announce that from nearly 3,400 publications by NIEHS researchers and grantees in 2023, Sciome has had one paper selected. Foley

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Corporate Address

2 Davis Drive
Research Triangle Park, NC 27709, USA

Office Location

1920 E NC 54 Hwy, Suite 510 & 520
Durham, NC 27713, USA

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